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MOTS-C MO
Research peptide

MOTS-C

A mitochondrial-derived peptide studied for its role in cellular energy regulation and metabolic homeostasis. 40 mg lyophilized vial, 2–8 °C storage.

Plain-language overview not yet generated.

Research Metrics 2026-06-16 · Editorial assessment · Not medical advice

What is MOTS-C?

MOTS-C (Mitochondrial Open reading frame of the twelve S rRNA-c) is a mitochondrial-derived peptide (MDP) encoded within the 12S rRNA gene of mitochondrial DNA. It is studied for its role in regulating cellular energy metabolism and homeostasis.

Research use only. Not for human or veterinary consumption. This page is for educational and informational purposes only.

Mechanism of action

MOTS-C acts as a metabolic regulator. Research indicates it translocates to the nucleus in response to metabolic stress, where it interacts with regulatory sequences to modulate gene expression related to energy metabolism. It is also studied in the context of mitochondria-to-nucleus signalling.

Presentation

Each vial contains 40 mg of lyophilized MOTS-C peptide. Reconstitution requires bacteriostatic water. Use the reconstitution calculator for an educational walkthrough of the math involved.

Storage

Store at 2–8 °C, protected from light. Once reconstituted, use within the timeframe established in your research protocol.

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